PT - JOURNAL ARTICLE AU - Ellis, H. A. AU - Stanworth, D. R. AU - Ratcliff, P. TI - Physico-chemical and immunological observations on the abnormal proteins in three patients with cryoglobulinaemia AID - 10.1136/jcp.14.2.179 DP - 1961 Mar 01 TA - Journal of Clinical Pathology PG - 179--184 VI - 14 IP - 2 4099 - http://jcp.bmj.com/content/14/2/179.short 4100 - http://jcp.bmj.com/content/14/2/179.full SO - J Clin Pathol1961 Mar 01; 14 AB - Three new cases of cryoglobulinaemia are described, and in each case the presence of the cryoglobulin appeared to be unrelated to the clinical manifestations. Although when examined by paper electrophoresis the abnormal proteins behaved uniformly as normal gamma globulins, marked differences in nature were revealed when ultracentrifugal and immunological analyses were made. One patient had an abnormal protein which behaved both as a cryoglobulin and as a macroglobulin.