RT Journal Article
SR Electronic
T1 Physico-chemical and immunological observations on the abnormal proteins in three patients with cryoglobulinaemia
JF Journal of Clinical Pathology
JO J Clin Pathol
FD BMJ Publishing Group Ltd and Association of Clinical Pathologists
SP 179
OP 184
DO 10.1136/jcp.14.2.179
VO 14
IS 2
A1 Ellis, H. A.
A1 Stanworth, D. R.
A1 Ratcliff, P.
YR 1961
UL http://jcp.bmj.com/content/14/2/179.abstract
AB Three new cases of cryoglobulinaemia are described, and in each case the presence of the cryoglobulin appeared to be unrelated to the clinical manifestations. Although when examined by paper electrophoresis the abnormal proteins behaved uniformly as normal gamma globulins, marked differences in nature were revealed when ultracentrifugal and immunological analyses were made. One patient had an abnormal protein which behaved both as a cryoglobulin and as a macroglobulin.