RT Journal Article
SR Electronic
T1 Serum glutamate dehydrogenase is not a reliable marker of liver cell necrosis in alcoholics.
JF Journal of Clinical Pathology
JO J Clin Pathol
FD BMJ Publishing Group Ltd and Association of Clinical Pathologists
SP 207
OP 210
DO 10.1136/jcp.35.2.207
VO 35
IS 2
A1 Jenkins, W J
A1 Rosalki, S B
A1 Foo, Y
A1 Scheuer, P J
A1 Nemesanszky, E
A1 Sherlock, S
YR 1982
UL http://jcp.bmj.com/content/35/2/207.abstract
AB Serum glutamate dehydrogenase (EC 1.4.1.3.) activity was measured in 73 hospital patients who had a history of chronic alcohol abuse and who all had a liver biopsy performed. High levels of serum GDH activity occurred in those patients with recent excess alcohol consumption independently of the underlying liver histology, and did not discriminate between those patients with and those without alcoholic hepatitis.