Positivity rate of both AC and NSCLC-NOS histology cases
Biomarker | Result | AC | NSCLC-NOS | P value* | AC+NSCLC-NOS | |||
n | % | n | % | n | % | |||
ALK | Positive | 79 | 3.4 | 6 | 2.9 | 0.854 | 85 | 3.4 |
Negative | 2232 | 96.6 | 200 | 97.1 | 2432 | 96.6 | ||
EGFR | Positive | 387 | 14.6 | 7 | 2.8 | <0.001 | 394 | 13.6 |
Negative | 2261 | 85.4 | 244 | 97.2 | 2505 | 86.4 | ||
PD-L1 | Positive | 822 | 48.7 | 91 | 54.2 | 0.204 | 913 | 49.2 |
Negative | 866 | 51.3 | 77 | 45.8 | 943 | 50.8 | ||
ROS1 | Positive | 33 | 2.0 | 2 | 1.5 | 0.909 | 35 | 2.0 |
Negative | 1585 | 98.0 | 132 | 98.5 | 1717 | 98.0 |
*P value determined by the χ2 test.
AC, adenocarcinoma; ALK, anaplastic lymphoma kinase; EGFR, epidermal growth factor receptor; NSCLC-NOS, non-small cell lung cancer–not otherwise specified; PD-L1, programmed death ligand-1; ROS1, c-ros oncogene 1.