Logistic regression model 1 for the testing rate
ALK | EGFR | PD-L1 | ROS1 | |||||
OR (95% CI) | P value | OR (95% CI) | P value | OR (95% CI) | P value | OR (95% CI) | P value | |
Sample type* (ref. biopsy) | ||||||||
Cell block | 0.84 (0.62 to 1.17) | 0.291 | 1.41 (0.93 to 2.23) | 0.121 | 0.44 (0.35 to 0.56) | <0.001 | 0.77 (0.61 to 0.97) | 0.026 |
FNA | 0.16 (0.12 to 0.22) | <0.001 | 2.89 (1.44 to 6.88) | 0.007 | 0.03 (0.02 to 0.05) | <0.001 | 0.24 (0.17 to 0.33) | <0.001 |
Surgical piece | 0.66 (0.52 to 0.85) | 0.001 | 1.10 (0.80 to 1.55) | 0.568 | 0.62 (0.51 to 0.75) | <0.001 | 0.97 (0.79 to 1.18) | 0.726 |
Others | 0.20 (0.15 to 0.26) | <0.001 | 2.2 (1.28 to 4.10) | 0.008 | 0.17 (0.13 to 0.22) | <0.001 | 0.33 (0.26 to 0.44) | <0.001 |
NSCLC-NOS (ref. adenocarcinoma) | 0.93 (0.68 to 1.29) | 0.666 | 1.06 (0.68 to 1.72) | 0.806 | 1.31 (0.99 to 1.75) | 0.062 | 0.87 (0.68 to 1.13) | 0.296 |
Hosmer-Lemeshow, p value | >0.999 | 0.957 | 0.968 | 0.998 | ||||
AUROC (95% CI) | 0.65 (0.62 to 0.67) | 0.559 (0.530 to 0.589) | 0.673 (0.655 to 0.691) | 0.588 (0.569 to 0.606) |
The results of the Hosmer-Lemeshow test and the AUROC are in italics to differentiate them from the ORs.
*Category ‘others’ includes blood samples.
ALK, anaplastic lymphoma kinase; AUROC, area under receiver operating characteristic curve; EGFR, epidermal growth factor receptor; FNA, fine-needle aspiration; NSCLC-NOS, non-small cell lung cancer–not otherwise specified; PD-L1, programmed death ligand-1; ref., reference; ROS1, c-ros oncogene 1.