Concordance between microscope versus medical device and microscope versus commercial device
| Microscope vs MG monitor | Microscope vs PG monitor | Microscope vs COTS monitor | |
| Main diagnosis (κ) | 1 | 1 | 1 |
| Secondary diagnosis (κ) | 1 | 1 | 0.96 (0.87 to 1) |
| Score | |||
| IgA MEST-C (r) | 0.98 (0.83 to 1) | 0.98 (0.83 to 1) | 0.91 (0.76 to 1) |
| ANCA vasculitis (κ) | 0.93 (0.77 to 1) | 0.93 (0.77 to 1) | 0.86 (0.64 to 1) |
| LN class (κ) | 1 | 0.5 (0 to 1) | 0.5 (0 to 1) |
| DN class (κ) | 1 | 1 | 1 |
| Amyloid type (κ) | 1 | 1 | 1 |
| Glomeruli (r) | |||
| Total | 0.99 (0.85 to 1) | 0.99 (0.84 to 1) | 0.95 (0.80 to 1) |
| Global sclerosis | 1 (0.85 to 1) | 0.99 (0.94 to 1) | 0.94 (0.79 to 1) |
| Seg sclerosis | 0.99 (0.85 to 1) | 0.99 (0.84 to 1) | 0.68 (0.53 to 0.83) |
| Endo hypercell | 1 (0.85 to 1) | 1 (0.85 to 1) | 1 (0.85 to 1) |
| Extra hypercell | 1 (0.85 to 1) | 0.99 (0.85 to 1) | 0.83 (0.68 to 0.98) |
| % IFTA (r) | 0.98 (0.84 to 1) | 0.98 (0.83 to 1) | 0.9 (0.76 to 1) |
| AS (0–3) (r) | 0.95 (0.81 to 1) | 0.90 (0.76 to 1) | 0.78 (0.64 to 0.93) |
| IF (0 vs any +) (r) | |||
| IgG | 1 (0.85 to 1) | 0.97 (0.83 to 1) | 0.98 (0.83 to 1) |
| IgA | 1 (0.85 to 1) | 0.95 (0.75 to 1) | 1 (0.85 to 1) |
| IgM | 1 (0.85 to 1) | 0.94 (0.84 to 1) | 1 (0.85 to 1) |
| C3 | 1 (0.85 to 1) | 0.94 (0.79 to 1) | 0.85 (0.70 to 0.99) |
| C1q | 1 (0.85 to 1) | 0.97 (0.82 to 1) | 0.92 (0.78 to 1) |
| Kappa | 0.99 (0.84 to 1) | 0.96 (0.81 to 1) | 0.96 (0.81 to 1) |
| Lambda | 1 (0.85 to 1) | 0.98 (0.83 to 1) | 0.96 (0.81 to 1) |
Cohen’s kappa (κ) was used for discrete variables, Pearson correlation coefficient (r) for continuous ones.
AS, arteriosclerosis; COTS, consumer-off-the-shelf; DN, diabetic nephropathy; Endo hypercell, endocapillary hypercellularity; Extra hypercell, extracapillary hypercellularity; IF, immunofluorescence; IFTA, interstitial fibrosis and tubular atrophy; LN, lupus nephritis; MG, medical grade; PG, professional grade; Seg sclerosis, segmental sclerosis.