Table 1

Overall characteristics of the cohort

VariableNo (%)
Age at diagnosis
<18 years19 (47.5)
Median 9.6
Range 1.2–17.6
≥18 years21 (52.5)
Median 37
Range 18.9–89.2
Gender
 Male25 (62.5)
 Female15 (37.5)
Tumour site
 Cerebral hemispheres27 (67.5)
 Diencephalon3 (7.5)
 Cerebellum7 (17.5)
 Brain stem3 (7.5)
Integrated diagnosis WHO 2021
Circumscribed astrocytic glioma
  PA9 (22.5)
  PXA4 (10)
Paediatric-type diffuse LGG
  PLNTY3 (7.5)
  DLGG, MAPK4 (10)
  Angiocentric glioma1 (2.5)
Paediatric-type diffuse HGG
  Infant-type hemispheric glioma*2 (5)
Adult-type diffuse glioma
  GBM9 (22.5)
  ODG1 (2.5)
  Astrocytoma1 (2.5)
Glioneuronal tumour
  GG2 (5)
 Not elsewhere classified4 (10)
Histological grade
 Low (1 and 2)24 (60)
 High (3 and 4)16 (40)
Total 40
  • *Included one low grade and one high grade.

  • DLGG, MAPK, diffuse low-grade glioma MAPK pathway-altered; GBM, glioblastoma; GG, ganglioglioma; HGG, high-grade glioma; LGG, low-grade glioma; ODG, oligodendroglioma IDH-mutant 1p/19q-codeleted; PA, pilocytic astrocytoma; PLNTY, polymorphous low-grade neuroepithelial tumour of the young; PXA, pleomorphic xanthoastrocytoma.