Overall characteristics of the cohort
Variable | No (%) |
Age at diagnosis | |
<18 years | 19 (47.5) |
Median 9.6 | |
Range 1.2–17.6 | |
≥18 years | 21 (52.5) |
Median 37 | |
Range 18.9–89.2 | |
Gender | |
Male | 25 (62.5) |
Female | 15 (37.5) |
Tumour site | |
Cerebral hemispheres | 27 (67.5) |
Diencephalon | 3 (7.5) |
Cerebellum | 7 (17.5) |
Brain stem | 3 (7.5) |
Integrated diagnosis WHO 2021 | |
Circumscribed astrocytic glioma | |
PA | 9 (22.5) |
PXA | 4 (10) |
Paediatric-type diffuse LGG | |
PLNTY | 3 (7.5) |
DLGG, MAPK | 4 (10) |
Angiocentric glioma | 1 (2.5) |
Paediatric-type diffuse HGG | |
Infant-type hemispheric glioma* | 2 (5) |
Adult-type diffuse glioma | |
GBM | 9 (22.5) |
ODG | 1 (2.5) |
Astrocytoma | 1 (2.5) |
Glioneuronal tumour | |
GG | 2 (5) |
Not elsewhere classified | 4 (10) |
Histological grade | |
Low (1 and 2) | 24 (60) |
High (3 and 4) | 16 (40) |
Total | 40 |
*Included one low grade and one high grade.
DLGG, MAPK, diffuse low-grade glioma MAPK pathway-altered; GBM, glioblastoma; GG, ganglioglioma; HGG, high-grade glioma; LGG, low-grade glioma; ODG, oligodendroglioma IDH-mutant 1p/19q-codeleted; PA, pilocytic astrocytoma; PLNTY, polymorphous low-grade neuroepithelial tumour of the young; PXA, pleomorphic xanthoastrocytoma.